منابع مشابه
Macromolecule-Assisted de novo Protein Folding
In the processes of protein synthesis and folding, newly synthesized polypeptides are tightly connected to the macromolecules, such as ribosomes, lipid bilayers, or cotranslationally folded domains in multidomain proteins, representing a hallmark of de novo protein folding environments in vivo. Such linkage effects on the aggregation of endogenous polypeptides have been largely neglected, altho...
متن کاملObservation of Single-Protein and DNA Macromolecule Collisions on Ultramicroelectrodes.
Single-molecule detection is the ultimate sensitivity in analytical chemistry and has been largely unavailable in electrochemical analysis. Here, we demonstrate the feasibility of detecting electrochemically inactive single biomacromolecules, such as enzymes, antibodies, and DNA, by blocking a solution redox reaction when molecules adsorb and block electrode sites. By oxidizing a large concentr...
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A cross-linked polyethyleneimine polymer containing the[ZnWZn2(H2O)2(ZnW9O34)2] poly-oxometalate was prepared from branched polyethyleneimine(Mw ) 600), the polyoxometalate, and an-octylamine-epichlorohydrin cross-linking reagent. This catalytic assembly was active for the selectiveoxidation of 2-alkanols to 2-alkanones with aqueous H2O2 with reactions presumably occurring a...
متن کاملDimensionality Reduction and Prediction of the Protein Macromolecule Dissolution Profile
A suitable regression model for predicting the dissolution profile of Poly (lactic-co-glycolic acid) (PLGA) microand nanoparticles can play a significant role in pharmaceutical/medical applications. The rate of dissolution of proteins is influenced by several factors and taking all such influencing factors into account, we have a dataset in hand with three hundred input features. Therefore, a p...
متن کاملA synthetic macromolecule for sentinel node detection: (99m)Tc-DTPA-mannosyl-dextran.
UNLABELLED We report the synthesis and preliminary biologic testing of a synthetic macromolecule, (99m)Tc-diethylenetriaminepentaacetic acid (DTPA)--mannosyl-dextran, for sentinel node detection. METHODS Synthesis started with a 2-step process that attaches a high density of amino-terminated leashes to a dextran backbone. Allyl-bromide was reacted with pharmaceutical-grade dextran to yield al...
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ژورنال
عنوان ژورنال: Kobunshi
سال: 1986
ISSN: 0454-1138,2185-9825
DOI: 10.1295/kobunshi.35.954